SynBioBeta Speaker

Jacob Glanville

Centivax

CEO

Jacob Glanville is a serial biotechnology entrepreneur, and value creator. He built and sold his first company Distributed Bio from founding in March of 2012 to a $104M dollar sale to Charles River Laboratories in December of 2020. During that period, he developed the core business model, grew and organized the research teams, and established the technology IP that enabled Distributed Bio to become profitable without investment and scale to 36 programs per year by the year of acquisition (beating Adimab in productivity). As part of the acquisition agreement, he founded Centivax Inc and spun-out his incubated IP for universal vaccines vaccines and broad-spectrum antibodies into Centivax, where he is now CEO. Prior to Distributed Bio, he was a Principal Scientist at Pfizer, where he developed multiple seminal methods in repertoire sequencing, synthetic antibody library design, for which he was awarded the 2010 Pfizer Achievement award. Prior to that, he worked at the Berkeley Phylogenomics Group, developing algorithms for analysis of rapidly evolving pathogens. Prior to that, he did some software development freelance work but also worked restaurant jobs in the service industry, interfacing with the public.Growing up watching his parents grow a successful hotel and restaurant business (La Posada de Santiago) in Guatemala in a Tzutujil village during a civil war, he was happy to find running a biotechnology startup to be similar in many respects, with many of the lessons learned in team management, product refinement, client recruitment and haggling to be surprisingly translatable. As a teenager, when his father became extremely ill in 1995-1996, he dropped out of highschool temporarily to run the business of 44 employees until his father recovered. From 2012-2019, he nurtured the vision of universal vaccines through the creation of a profitable business to support the work, the building of an animal facility in Guatemala to prove the technology, a collaboration with the University of San Carlos, supported an international research team over 4 years to prove the technology in-vivo, and managed to gather a team of remarkable scientists from USF, Pfizer, Genentech and other places who agreed to join and participate in manifesting the vision.

SynBioBeta 2026 Tickets are Live

Confirmed Speakers

Sessions Featuring

Jacob

This Year

Fireside Chat

8:35 AM

-

8:50 AM

Human Health

Programmable Immunity: Engineering the Universal Antivenom

For over a century, antivenoms have relied on serum extraction from animals — a process that’s costly, inconsistent, and limited to specific snake species. Today, advances in synthetic biology and antibody engineering are pointing toward a different future: a universal antivenom capable of neutralizing toxins across the world’s deadliest snakes. This session dives into the science and story behind this breakthrough — from the man who endured more than 200 bites to generate a unique immune response, to the researchers using those antibodies to design broad-spectrum, recombinant therapies. Together, they’re charting the path from survival experiment to programmable immunity.

Purchase Pass

Fireside Chat

8:35 AM

-

8:50 AM

Human Health

Programmable Immunity: Engineering the Universal Antivenom

For over a century, antivenoms have relied on serum extraction from animals — a process that’s costly, inconsistent, and limited to specific snake species. Today, advances in synthetic biology and antibody engineering are pointing toward a different future: a universal antivenom capable of neutralizing toxins across the world’s deadliest snakes. This session dives into the science and story behind this breakthrough — from the man who endured more than 200 bites to generate a unique immune response, to the researchers using those antibodies to design broad-spectrum, recombinant therapies. Together, they’re charting the path from survival experiment to programmable immunity.

Purchase Pass

TBD

Session lineup still growing

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Featuring

Speaker Coming Soon

Fireside Chat

12:00 AM

-

8:30 AM

Human Health

From Cells to Patients: Solving the Scale Mismatch in Virtual Biology

Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?

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Featuring

Speaker Coming Soon

Previous Speakers Include