
SynBioBeta Speaker
Juan Cassini
BioClé
CEO
Juan Cassini is cofounder and CEO of BioClé, a biotech company building a next generation delivery platform using bacterial extracellular vesicles. BioClé is focused on improving how bioactive compounds reach cells, unlocking better efficacy for applications in human health and nutrition.Before BioClé, Juan worked at one of the top venture capital law firms in Latin America, advising both startups and funds on fundraising and deal structuring, with a front row seat to how capital is deployed and high growth companies are built. He is also a second time founder, having previously co founded ByCM, a communications company working with major players in sports and entertainment.
SynBioBeta 2026 Tickets are Live
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Human Health
From Cells to Patients: Solving the Scale Mismatch in Virtual Biology
Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?
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