SynBioBeta Speaker

Justin Eyquem

UCSF

Associate Professor

Justin Eyquem, PhD, is an Associate Professor of Medicine at the University of California, San Francisco, and an Investigator at the Gladstone–UCSF Institute of Genomic Immunology and the Parker Institute for Cancer Immunotherapy. He earned his PhD in molecular biology from Université Paris VII and completed postdoctoral training with Michel Sadelain at Memorial Sloan Kettering Cancer Center. He joined UCSF in 2019 as a Parker Fellow and became an Assistant Professor in 2021. His research focuses on precisely engineering T cells to improve cancer immunotherapy and enable new treatments for immune and genetic diseases. His laboratory has pioneered genome-editing strategies for CAR-T cells, including site-specific integration and multiplex editing, and has developed platforms to reprogram T cell function both ex vivo and directly in vivo. His work spans fundamental discovery through clinical translation, with a strong emphasis on scalable, next-generation cell therapy manufacturing. He also directs a dedicated preclinical team at UCSF that systematically benchmarks engineered T cell designs to accelerate their advancement into first-in-human trials. This includes an investigator-initiated CAR-T trial for multiple myeloma launching in early 2026.

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