
SynBioBeta Speaker
Po Bronson
SOSV
General Partner
Po is a General Partner at SOSV and Managing Director of SOSV SF. He is passionate about reconceptualizing complex challenges into more elegant forms in order to broaden understanding and highlight priorities.Po is a longtime science journalist honored with nine national awards, and author of seven bestselling books that are available in 28 languages worldwide. His work has been cited in 185 academic journals and 503 books. His background is in Economics. He learned finance at Credit Suisse and consulting at a division of Arthur Andersen. Prior to SOSV SF, he spent four years as a Futurist with Attention Span Media, consulting corporate innovation efforts for globally recognized brands.Most recently, Po is the author of Decoding the World: A Roadmap for the Questioner, published by Twelve Books, a division of the Hachette Publishing Group.
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Human Health
From Cells to Patients: Solving the Scale Mismatch in Virtual Biology
Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?
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