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SynBioBeta Speaker

Zach Cogan

Nucleate HQ

President Emeritus

Zach is a PhD Candidate at UCSF and Altos Labs, where he is co-advised by Peter Walter and Adam Frost. His doctoral research focuses on the mechanisms of translational control and cellular stress. Prior to his graduate studies, Zach worked in the lab of Jonathan Weissman, where he contributed to the development of CRISPRoff technology. Dedicated to the life science innovation community, Zach co-founded Nucleate Bay Area in 2020 and served as Co-President and EVP of Partnerships for Nucleate HQ from 2022-2026. In these leadership roles, he focused on bridging the gap between academia and industry, securing strategic partnerships with several leading pharmaceutical companies to support the translation of rigorous science into new therapeutics and tools.

Sessions Featuring

Zach

This Year

TBD

Session lineup still growing

Featuring

Speaker Coming Soon

Fireside Chat

12:00 AM

-

8:30 AM

Human Health

From Cells to Patients: Solving the Scale Mismatch in Virtual Biology

Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?

Featuring

Speaker Coming Soon

Previous Speakers Include