SynBioBeta Speaker
Zachary Gobst
Leapcure
CEO
Founder and CEO of Leapcure, the leader in patient engagement and recruitment for clinical trials. Leapcure’s equitable and empathetic service accelerates research while empowering patient advocacy. Hundreds of studies and millions of patients across more than 50 countries have used Leapcure to average 62% of study participation. Zach is also a lover of Tufte data visualization, podcasting with anyone, sleep, Fulham FC and Indiana University football (at least recently).
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SynBioBeta 2026 Tickets are Live
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Human Health
From Cells to Patients: Solving the Scale Mismatch in Virtual Biology
Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?
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