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SynBioBeta Speaker

Miki Heller

Brain Repair Foundation

Co-founder

Miki is a strategy and operations leader, and a mother of four whose work now sits at the intersection of rare disease, AI, and brain repair. She studied aerospace engineering at Cal Poly, began her career teaching middle school math through Teach For America, and later earned a joint MPP/MBA from the Harvard Kennedy School and Harvard Business School. Most recently, she worked at Astranis, where she spent eight years as Vice President of Operations and Strategy helping scale the company and leading all core business functions.



Miki’s entry into biology and medicine came through her son Levi. After typical early development, Levi began a slow regression at age two and a half, eventually losing language, social engagement, motor skills, and the ability to follow directions. After years of advocating for deeper testing, Miki and her husband Jake learned that Levi has DEE-SWAS, a rare epileptic encephalopathy causing near-continuous abnormal brain activity.



That diagnosis launched their work to stop Levi’s seizures, identify root cause, and pursue brain repair. Miki and her husband Jake are now building the Brain Repair Foundation to support research, drug repurposing, neuromodulation, and other approaches that may help Levi and others living with neurological injury.

Sessions Featuring

Miki

This Year

Breakout Session

3:30 PM

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4:15 PM

Human Health

When Patients Become Pioneers: Parents Driving the Search for Rare Disease Cures

When a child has a rare disease with no treatment or cure, some parents do far more than advocate: they learn the science, build networks, fund research, and help create entirely new paths to therapy. This panel brings together parents who have become active participants in the search for answers, not because they planned to, but because time left them no alternative. For a SynBioBeta audience of researchers, founders, and builders, this is a chance to hear directly from the people living on the receiving end of scientific progress — and scientific delay. It is also an invitation: if you are working on a tool, platform, or idea that could help, these families are ready to collaborate.

Breakout Session

3:30 PM

-

4:15 PM

Human Health

When Patients Become Pioneers: Parents Driving the Search for Rare Disease Cures

When a child has a rare disease with no treatment or cure, some parents do far more than advocate: they learn the science, build networks, fund research, and help create entirely new paths to therapy. This panel brings together parents who have become active participants in the search for answers, not because they planned to, but because time left them no alternative. For a SynBioBeta audience of researchers, founders, and builders, this is a chance to hear directly from the people living on the receiving end of scientific progress — and scientific delay. It is also an invitation: if you are working on a tool, platform, or idea that could help, these families are ready to collaborate.

TBD

Session lineup still growing

Featuring

Speaker Coming Soon

Fireside Chat

12:00 AM

-

8:30 AM

Human Health

From Cells to Patients: Solving the Scale Mismatch in Virtual Biology

Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?

Featuring

Speaker Coming Soon

Previous Speakers Include