Join us in
04 Days 05 H 43 Min 30 Sec
Join us in
04 Days 05 H 43 Min 30 Sec
Hyperscale Longevity
Rewriting the Code of Biology and Unlocking Longer, Healthier Lives.
May 5-8
2025
San Jose Convention Center
California, USA
May 5-8
2025
San Jose Convention Center
California, USA


About the event
From cellular reprogramming and senescence-targeting therapies to advanced diagnostics and aging clocks, the field of longevity is accelerating at an unprecedented pace. Scientists and entrepreneurs are pushing the boundaries of what it means to grow old—turning age into a modifiable variable rather than an inevitable decline.
At the intersection of synthetic biology, regenerative medicine, and AI, new tools and interventions are emerging to extend healthspan, delay age-related diseases, and potentially reverse biological aging. Whether through epigenetic reprogramming, engineered immune cells, or next-gen nutraceuticals, the longevity revolution is here.
This is where new paradigms in health, vitality, and human potential are no longer constrained by the limits of time.
Top Sessions
1
-
Unbound Biology: Cracking the Age Code
What if aging were optional? In this provocative session, Bryan Johnson (Founder, Don't Die) and Jason Kelly (Co-Founder & CEO, Ginkgo Bioworks) explore how synthetic biology, data-driven optimization, and radical self-experimentation are converging to rewrite the rules of human longevity. From cellular reprogramming to biological automation, they’ll discuss what it takes to crack the age code—and what the future of ageless living might look like.
[…]
2
-
A Rallying Call to Work on Longevity
In this keynote, Peter Diamandis, will issue a rallying call to redefine how we think about aging and harness the synergy of biotech, AI, and bold thinking to push the boundaries of healthy lifespan extension. He will draw on insights from The Longevity Insider’s Guide to present transformative solutions poised to disrupt the healthcare landscape. He will spotlight how entrepreneurs, researchers, and investors can join forces to accelerate breakthroughs and overcome the most urgent challenges in aging. By shifting from scarcity to possibility, he will show how collective innovation can usher in an era of unprecedented longevity, redefining what it means to thrive at every stage of life.
[…]
3
-
How Breakthroughs in Cellular Reprogramming Could Transform Aging
Epigenetic reprogramming has rapidly become the hottest area in longevity biotech, attracting unprecedented attention and billions in investment in just the last two years. Building on Shinya Yamanaka's Nobel Prize winning iPSC reprogramming, a new wave of biotech startups are now racing to extend the concept to therapeutically rejuvenate the cells in our bodies. This panel brings together the leading researchers and entrepreneurs of this field to explore the science and recent breakthroughs driving the excitement, the challenges of bringing these therapies to market, and the future of a field that could redefine what it means to age.
[…]
4
-
The Neural Frontier: Pioneering Tomorrow's Brain Technologies
The stuff of science fiction is becoming reality! These scientist and entrepreneurs are tackling the next generation of brain connectomics, advanced brain-computer interfaces, neuromodulation, and stem cell replacement. These technologies aim to treat specific disorders today, but will enable a path for us to become cyborgs and live longer.
[…]
5
-
Designing Biology for a Generation That Never Ages
What if aging wasn’t a fate, but a variable we could measure—and reprogram? In this visionary session, Alina Su, Founder & CEO of Generation Lab, reveals how next-gen bioengineering is unlocking the future of longevity. By quantifying organ-specific biological age and intervening via Therapeutic Plasma Exchange (TPE) with next-generation synthetic plasma, (No Blood Boys needed!) Generation Lab is pioneering a new class of aging entropy diagnostic with preventative therapies. Alina shares how we’re moving from reactive medicine to proactive self-optimization—where biology isn’t just observed, but engineered to help us live longer, stronger, and smarter.
[…]
6
-
Next-Gen Medicine: AI-Powered Advances Reshaping Human Therapeutics
Dive into the cutting-edge today, not just the promises of tomorrow. This dynamic breakout session features biotech visionaries actively leveraging machine learning and AI to transform the engineering of human therapeutics. Hear firsthand from industry pioneers pushing the boundaries—from accelerating drug target discovery to streamlining clinical development pipelines. Learn how advanced analytics and big data are already enhancing personalized medicine, boosting clinical success rates, and rapidly reshaping the future landscape of healthcare. Don't miss this inside look at the real-world innovations redefining what's possible in therapeutic discovery and precision medicine.
[…]
7
-
Space Therapies: Accelerating Biotech Solutions for Health Beyond Earth
Space is among the harshest and least hospitable environments for humans. Every human biological system is affected by the space environment. The biological stress has a deleterious impact on health and physical capabilities, and the extreme conditions and isolation take a significant toll on mental performance and behavior. By 2040, hundreds of people will be in space at any given time, and more than 80% of those are predicted to be private citizens; for the reliability, safety, health, and enjoyment of those private participants, new solutions and therapeutics are needed to maintain health and wellbeing.
[…]
8
-
Synthetic Biology Frontiers in Transplantation: Engineering Durable Therapeutic Solutions
This cutting-edge session explores the intersection of synthetic biology, materials science, and transplantation medicine to address key challenges in cell, tissue, and organ transplantation. We'll examine innovative approaches to enhance transplant durability, improve integration with host systems, and advance the field of regenerative medicine. Examples include: genetically engineered cells for enhanced survival, 3d-printed scaffolds and organoids, advances in xenotransplantation, and others.
[…]
9
-
Bio/acc and Biohack: The Science Behind the Hype
Bio/acc and Biohacking have both become popular movements on Twitter of late. This session brings together people who 'hype' them up and people who temper these sectors with science and point out flawed approaches. Get ready for a spicy conversation.
[…]
10
-
The Living Future: How SynBio, Genomics, and Regenerative Medicine are Transforming Human Health
Synthetic biology is blurring the lines between biology and technology, unlocking breakthroughs in regenerative medicine, biofabrication, and personalized healthcare. This panel brings together leading innovators who are shaping the future of human health. Join this session to explore the role of multidisciplinary technologies in healthcare. Understand how genomics, synthetic biology, and regenerative medicine are personalizing treatment and examine the ethical and practical challenges in deploying next-gen biotechnologies.
[…]
1
-
Unbound Biology: Cracking the Age Code
What if aging were optional? In this provocative session, Bryan Johnson (Founder, Don't Die) and Jason Kelly (Co-Founder & CEO, Ginkgo Bioworks) explore how synthetic biology, data-driven optimization, and radical self-experimentation are converging to rewrite the rules of human longevity. From cellular reprogramming to biological automation, they’ll discuss what it takes to crack the age code—and what the future of ageless living might look like.
[…]
2
-
A Rallying Call to Work on Longevity
In this keynote, Peter Diamandis, will issue a rallying call to redefine how we think about aging and harness the synergy of biotech, AI, and bold thinking to push the boundaries of healthy lifespan extension. He will draw on insights from The Longevity Insider’s Guide to present transformative solutions poised to disrupt the healthcare landscape. He will spotlight how entrepreneurs, researchers, and investors can join forces to accelerate breakthroughs and overcome the most urgent challenges in aging. By shifting from scarcity to possibility, he will show how collective innovation can usher in an era of unprecedented longevity, redefining what it means to thrive at every stage of life.
[…]
3
-
How Breakthroughs in Cellular Reprogramming Could Transform Aging
Epigenetic reprogramming has rapidly become the hottest area in longevity biotech, attracting unprecedented attention and billions in investment in just the last two years. Building on Shinya Yamanaka's Nobel Prize winning iPSC reprogramming, a new wave of biotech startups are now racing to extend the concept to therapeutically rejuvenate the cells in our bodies. This panel brings together the leading researchers and entrepreneurs of this field to explore the science and recent breakthroughs driving the excitement, the challenges of bringing these therapies to market, and the future of a field that could redefine what it means to age.
[…]
4
-
The Neural Frontier: Pioneering Tomorrow's Brain Technologies
The stuff of science fiction is becoming reality! These scientist and entrepreneurs are tackling the next generation of brain connectomics, advanced brain-computer interfaces, neuromodulation, and stem cell replacement. These technologies aim to treat specific disorders today, but will enable a path for us to become cyborgs and live longer.
[…]
5
-
Designing Biology for a Generation That Never Ages
What if aging wasn’t a fate, but a variable we could measure—and reprogram? In this visionary session, Alina Su, Founder & CEO of Generation Lab, reveals how next-gen bioengineering is unlocking the future of longevity. By quantifying organ-specific biological age and intervening via Therapeutic Plasma Exchange (TPE) with next-generation synthetic plasma, (No Blood Boys needed!) Generation Lab is pioneering a new class of aging entropy diagnostic with preventative therapies. Alina shares how we’re moving from reactive medicine to proactive self-optimization—where biology isn’t just observed, but engineered to help us live longer, stronger, and smarter.
[…]
6
-
Next-Gen Medicine: AI-Powered Advances Reshaping Human Therapeutics
Dive into the cutting-edge today, not just the promises of tomorrow. This dynamic breakout session features biotech visionaries actively leveraging machine learning and AI to transform the engineering of human therapeutics. Hear firsthand from industry pioneers pushing the boundaries—from accelerating drug target discovery to streamlining clinical development pipelines. Learn how advanced analytics and big data are already enhancing personalized medicine, boosting clinical success rates, and rapidly reshaping the future landscape of healthcare. Don't miss this inside look at the real-world innovations redefining what's possible in therapeutic discovery and precision medicine.
[…]
7
-
Space Therapies: Accelerating Biotech Solutions for Health Beyond Earth
Space is among the harshest and least hospitable environments for humans. Every human biological system is affected by the space environment. The biological stress has a deleterious impact on health and physical capabilities, and the extreme conditions and isolation take a significant toll on mental performance and behavior. By 2040, hundreds of people will be in space at any given time, and more than 80% of those are predicted to be private citizens; for the reliability, safety, health, and enjoyment of those private participants, new solutions and therapeutics are needed to maintain health and wellbeing.
[…]
8
-
Synthetic Biology Frontiers in Transplantation: Engineering Durable Therapeutic Solutions
This cutting-edge session explores the intersection of synthetic biology, materials science, and transplantation medicine to address key challenges in cell, tissue, and organ transplantation. We'll examine innovative approaches to enhance transplant durability, improve integration with host systems, and advance the field of regenerative medicine. Examples include: genetically engineered cells for enhanced survival, 3d-printed scaffolds and organoids, advances in xenotransplantation, and others.
[…]
9
-
Bio/acc and Biohack: The Science Behind the Hype
Bio/acc and Biohacking have both become popular movements on Twitter of late. This session brings together people who 'hype' them up and people who temper these sectors with science and point out flawed approaches. Get ready for a spicy conversation.
[…]
10
-
The Living Future: How SynBio, Genomics, and Regenerative Medicine are Transforming Human Health
Synthetic biology is blurring the lines between biology and technology, unlocking breakthroughs in regenerative medicine, biofabrication, and personalized healthcare. This panel brings together leading innovators who are shaping the future of human health. Join this session to explore the role of multidisciplinary technologies in healthcare. Understand how genomics, synthetic biology, and regenerative medicine are personalizing treatment and examine the ethical and practical challenges in deploying next-gen biotechnologies.
[…]
1
-
Unbound Biology: Cracking the Age Code
What if aging were optional? In this provocative session, Bryan Johnson (Founder, Don't Die) and Jason Kelly (Co-Founder & CEO, Ginkgo Bioworks) explore how synthetic biology, data-driven optimization, and radical self-experimentation are converging to rewrite the rules of human longevity. From cellular reprogramming to biological automation, they’ll discuss what it takes to crack the age code—and what the future of ageless living might look like.
[…]
2
-
A Rallying Call to Work on Longevity
In this keynote, Peter Diamandis, will issue a rallying call to redefine how we think about aging and harness the synergy of biotech, AI, and bold thinking to push the boundaries of healthy lifespan extension. He will draw on insights from The Longevity Insider’s Guide to present transformative solutions poised to disrupt the healthcare landscape. He will spotlight how entrepreneurs, researchers, and investors can join forces to accelerate breakthroughs and overcome the most urgent challenges in aging. By shifting from scarcity to possibility, he will show how collective innovation can usher in an era of unprecedented longevity, redefining what it means to thrive at every stage of life.
[…]
3
-
How Breakthroughs in Cellular Reprogramming Could Transform Aging
Epigenetic reprogramming has rapidly become the hottest area in longevity biotech, attracting unprecedented attention and billions in investment in just the last two years. Building on Shinya Yamanaka's Nobel Prize winning iPSC reprogramming, a new wave of biotech startups are now racing to extend the concept to therapeutically rejuvenate the cells in our bodies. This panel brings together the leading researchers and entrepreneurs of this field to explore the science and recent breakthroughs driving the excitement, the challenges of bringing these therapies to market, and the future of a field that could redefine what it means to age.
[…]
4
-
The Neural Frontier: Pioneering Tomorrow's Brain Technologies
The stuff of science fiction is becoming reality! These scientist and entrepreneurs are tackling the next generation of brain connectomics, advanced brain-computer interfaces, neuromodulation, and stem cell replacement. These technologies aim to treat specific disorders today, but will enable a path for us to become cyborgs and live longer.
[…]
5
-
Designing Biology for a Generation That Never Ages
What if aging wasn’t a fate, but a variable we could measure—and reprogram? In this visionary session, Alina Su, Founder & CEO of Generation Lab, reveals how next-gen bioengineering is unlocking the future of longevity. By quantifying organ-specific biological age and intervening via Therapeutic Plasma Exchange (TPE) with next-generation synthetic plasma, (No Blood Boys needed!) Generation Lab is pioneering a new class of aging entropy diagnostic with preventative therapies. Alina shares how we’re moving from reactive medicine to proactive self-optimization—where biology isn’t just observed, but engineered to help us live longer, stronger, and smarter.
[…]
6
-
Next-Gen Medicine: AI-Powered Advances Reshaping Human Therapeutics
Dive into the cutting-edge today, not just the promises of tomorrow. This dynamic breakout session features biotech visionaries actively leveraging machine learning and AI to transform the engineering of human therapeutics. Hear firsthand from industry pioneers pushing the boundaries—from accelerating drug target discovery to streamlining clinical development pipelines. Learn how advanced analytics and big data are already enhancing personalized medicine, boosting clinical success rates, and rapidly reshaping the future landscape of healthcare. Don't miss this inside look at the real-world innovations redefining what's possible in therapeutic discovery and precision medicine.
[…]
7
-
Space Therapies: Accelerating Biotech Solutions for Health Beyond Earth
Space is among the harshest and least hospitable environments for humans. Every human biological system is affected by the space environment. The biological stress has a deleterious impact on health and physical capabilities, and the extreme conditions and isolation take a significant toll on mental performance and behavior. By 2040, hundreds of people will be in space at any given time, and more than 80% of those are predicted to be private citizens; for the reliability, safety, health, and enjoyment of those private participants, new solutions and therapeutics are needed to maintain health and wellbeing.
[…]
8
-
Synthetic Biology Frontiers in Transplantation: Engineering Durable Therapeutic Solutions
This cutting-edge session explores the intersection of synthetic biology, materials science, and transplantation medicine to address key challenges in cell, tissue, and organ transplantation. We'll examine innovative approaches to enhance transplant durability, improve integration with host systems, and advance the field of regenerative medicine. Examples include: genetically engineered cells for enhanced survival, 3d-printed scaffolds and organoids, advances in xenotransplantation, and others.
[…]
9
-
Bio/acc and Biohack: The Science Behind the Hype
Bio/acc and Biohacking have both become popular movements on Twitter of late. This session brings together people who 'hype' them up and people who temper these sectors with science and point out flawed approaches. Get ready for a spicy conversation.
[…]
10
-
The Living Future: How SynBio, Genomics, and Regenerative Medicine are Transforming Human Health
Synthetic biology is blurring the lines between biology and technology, unlocking breakthroughs in regenerative medicine, biofabrication, and personalized healthcare. This panel brings together leading innovators who are shaping the future of human health. Join this session to explore the role of multidisciplinary technologies in healthcare. Understand how genomics, synthetic biology, and regenerative medicine are personalizing treatment and examine the ethical and practical challenges in deploying next-gen biotechnologies.
[…]
It is really a technological cornucopia of new ideas and deployments of technology.
Chris Mason
Professor, Cornell University
It’s been a tremendously exciting conference for me, and very different to what I've been to before. Everyone's been extraordinary and generous with their time and ideas.
Drew Berry
Molecular Animator
Taking the SynBioBeta stage is an unmatched opportunity to share our work with the people who truly comprehend its enormity. It is the ultimate gathering for those at the forefront of the synthetic biology revolution.
Jodi Barrientos
CEO, Ribbon Bio
Every year there's more. There's more companies, there's more technologies, more applications of technologies.
Julianna LeMieux
Deputy Editor in Chief, GEN
This is an amazing conference, and a great chance to see a snapshot of the industry. It's a place where you can make a lot of little molecular interactions and collisions.
Kate Rubins
NASA Astronaut
I first came to SynBioBeta to learn more about the field. I stayed for the community. There is no better place to go learn and network.
Kristin Ellis
Partner, Lowercarbon Capital
An extraordinary and extraordinarily important conference, the only conference where I feel I learn a lot. SynBioBeta is my tribe!
Martine Rothblatt
Founder & CEO, United Therapeutics
A conference where every single person I met was a) brilliant b) had a new fresh tech idea and c) could have a huge positive transformational impact on the world and d) could communicate all this clearly and concisely.
Mary Lou Jepsen
Founder, Openwater
Easily my favorite and most stimulating conference. Every day I was pleasantly surprised by some nugget of insight. Coming from another field I was apprehensive, but the SynBioBeta community had a meaningful impact on me, and made me feel instantly welcome.
Mickey McManus
Senior Advisor & Executive Coach, BCG
I cannot think of a better place where I can find new talent each year to work with our teams.
Paul Stamets
Founder & Member, Fungi Perfecti

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