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SynBioBeta Speaker

Anastasia Shindyapina

Retro Biosciences

Team Lead

Anastasia received her PhD from Lomonosov Moscow State University, focusing on both molecular biology and bioinformatics. She later worked in Vadim Gladyshev’s group at Harvard Medical School, where she studied the mechanisms of immune system aging and identified interventions extending lifespan in mice. She joined Retro Biosciences with the goal of translating longevity therapies from preclinical models to patients.At Retro, her and her team develops stem cell therapies aimed at improving immune function in elderly patients with chronic and acute hematological conditions. Their approach produces young-like hematopoietic stem cells that have potential to reconstruct the entire human immune system and can be generated from patient’s own cells.

Sessions Featuring

Anastasia

This Year

Femtech

12:45 PM

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1:30 PM

Human Health

Epigenetics and Stem Cells reprogramming / evidence based longevity

Aging is not a destiny. It is a program. And programs can be rewritten.Epigenetic clocks are now precise enough to measure biological age down to the tissue level. Stem cell engineering is restoring function in systems once thought irreversible. Longevity science — for the first time in its history — has the tools to match its ambitions.This chamber convenes the researchers doing the matching: scientists who have moved past the supplement stacks and the headlines, into the hard, exacting work of understanding what drives cellular aging — and what, with enough precision, can slow it, reverse it, or render it beside the point.

Femtech

12:45 PM

-

1:30 PM

Human Health

Epigenetics and Stem Cells reprogramming / evidence based longevity

Aging is not a destiny. It is a program. And programs can be rewritten.Epigenetic clocks are now precise enough to measure biological age down to the tissue level. Stem cell engineering is restoring function in systems once thought irreversible. Longevity science — for the first time in its history — has the tools to match its ambitions.This chamber convenes the researchers doing the matching: scientists who have moved past the supplement stacks and the headlines, into the hard, exacting work of understanding what drives cellular aging — and what, with enough precision, can slow it, reverse it, or render it beside the point.

TBD

Session lineup still growing

Featuring

Speaker Coming Soon

Fireside Chat

12:00 AM

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8:30 AM

Human Health

From Cells to Patients: Solving the Scale Mismatch in Virtual Biology

Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?

Featuring

Speaker Coming Soon

Previous Speakers Include