SynBioBeta Speaker
Gideon Lapidoth
Enzymit
CEO & Co-founder
I am the CEO & Co-Founder of Enzymit, where I lead strategy, partnerships, and company building around a cell-free biomanufacturing platform. Enzymit combines computational enzyme design, deep learning, and high-throughput discovery to develop controllable production systems for complex molecules.I hold a PhD in Computational Protein Design from the Weizmann Institute of Science and completed postdoctoral research in enzyme engineering under Prof. Dan Tawfik. At Enzymit, we have advanced the platform to kilogram-scale validation in hyaluronic acid production with industrial partners, and we are now focused on collaborations around industrial biotechnology, advanced biomanufacturing, scale-up, and commercialization of next-generation production technologies.
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Human Health
From Cells to Patients: Solving the Scale Mismatch in Virtual Biology
Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?
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