SynBioBeta Speaker
Mark Budde
Plasmidsaurus
Co-Founder & CEO
Mark Budde is Co-Founder and CEO of Plasmidsaurus, the company that sequences while you sleep. Mark is a synthetic biologist who couldn't stand how slow his experiments were going and how limiting the sequencing options were so he built the company he wished existed. Plasmidsaurus runs ten labs on three continents serving tens of thousands of biomedical researchers with the fastest DNA sequencing possible.
SynBioBeta 2026 Tickets are Live
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Human Health
From Cells to Patients: Solving the Scale Mismatch in Virtual Biology
Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?
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