SynBioBeta Speaker
Simon Kohl
Latent Labs
Founder & CEO
Dr. Simon Kohl is the founder and CEO of Latent Labs, a frontier AI lab that enables biotech and pharmaceutical companies to generate and optimize proteins. Simon previously started and co-led DeepMind's protein design team and was a senior research scientist on the Nobel Prize-winning AlphaFold2 project, where he developed the crucial pLDDT confidence quantification system now widely used to predict laboratory success in protein design. At Latent Labs, backed by $50M in total funding from investors including Radical Ventures, Sofinnova Partners, Google Chief Scientist Jeff Dean and CEO of Anthropic Dario Amodei, Simon leads a team innovating frontier models that use cutting-edge generative techniques to computationally create new therapeutic molecules like antibodies and enzymes. The company is focused on enabling partners at scale to tackle challenging targets, develop precision medicines, and accelerate development timelines through their AI protein design platform.
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Human Health
From Cells to Patients: Solving the Scale Mismatch in Virtual Biology
Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?
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