SynBioBeta Speaker
Sue Siegel
Align Technology
Board Director & Chairman
Sue Siegel is a seasoned board director, former CEO, and venture capitalist with a rare blend of governance expertise, commercial acumen, operational prowess, and innovation leadership across life sciences, healthcare, and technology. For more than 25 years, she has helped boards anticipate disruption, strengthen oversight, and unlock long-term value.
She currently serves on the boards of Align Technology, Illumina, and KFF (formerly Kaiser Family Foundation), and is Chairman of the Board of The Engine, built by MIT. Over her career, she has served on more than 20 public, private, and nonprofit boards with extensive Audit, Compensation, Nominating & Governance, Technology, Investment, and Special Committee experience—including multiple chair roles. Recognized on the NACD Directorship 100 in 2023 and 2024, she is widely regarded as an inspirational, pragmatic, and forward-thinking leader who blends strategic foresight with disciplined governance.
Her executive career includes serving as Chief Innovation Officer at GE, CEO of GE Ventures & Licensing, and CEO of Healthymagination, advancing investments and partnerships at the intersection of healthcare and technology. Previously, she was a General Partner at Mohr Davidow Ventures, leading life sciences and precision health investments, and President & Board Director of Affymetrix, where she led the company from a pre-revenue startup to a multi-billion-dollar, NASDAQ-listed global genomics leader—helping shape the field’s early growth and address emerging bioethical issues.
In public service, Sue has served on President Obama’s Precision Medicine Initiative Working Group, catalyzing the All of Us research program; was a founding board member of the National Center for Advancing Translational Sciences; and acted as a White House Fellows selection judge under multiple administrations. She also co-chairs Stanford Medicine’s Board of Fellows and serves on the Innovation Growth Board of Mass General Brigham.
Her leadership has been recognized by Fortune’s “34 Leaders Who Are Changing Health Care,”the Silicon Valley Business Journal’s “100 Most Influential Women in Silicon Valley,” Fierce Biotech’s “Top 10 Women in Medical Devices,” and the Global Corporate Venture Lifetime Achievement Award. An Aspen Institute Henry Crown Fellow, she is featured in the bestselling book Multipliers: How the Best Leaders Make Everyone Smarter and serves on the faculty of MIT Sloan School of Management.
