
SynBioBeta Speaker
Leroy Hood
ISB
Co-founder & Prof.
Dr. Lee Hood is a world-renowned scientist and recipient of the
National Medal of Science in 2011. Dr. Leroy Hood co-founded the
Institute for Systems Biology (ISB) in 2000 and served as its first
President from 2000-2017. In 2016, ISB affiliated with Providence St.
Joseph Health (PSJH) and Dr. Hood became PSJH’s Senior Vice President
and Chief Science Officer. He is also Chief Strategy Officer and
Professor at ISB. Dr. Hood is a member of the National Academy of
Sciences, the National Academy of Engineering, and the National
Academy of Medicine. Of the more than 6,000 scientists worldwide who
belong to one or more of these academies, Dr. Hood is one of only 20
people elected to all three. He is also in the Inventor Hall of Fame
for the automated DNA sequencer.
He received his MD from Johns Hopkins University School of Medicine
and his PhD in biochemistry from Caltech. Dr. Hood was a faculty
member at Caltech from 1967-1992, serving for 10 years as the Chair of
Biology. During this period, he and his colleagues developed four
sequencer and synthesizer instruments that paved the way for the Human
Genome Project’s successful mapping and understanding of the human
genome. He and his students also deciphered many of the complex
mechanisms of antibody diversification. 1992, Dr. Hood founded and
chaired the Department of Molecular Biotechnology at the University of
Washington, the first academic department devoted to
cross-disciplinary biology and individuals from this department
developed pioneering strategies in genomics, proteomics and cell
biology. Dr. Hood then in 2000 began pioneering many applications of
systems biology to ordinary biology and disease (neurodegeneration,
cancer). While at Systems biology, in 2014 he pioneered the study of
data-driven health in individuals (108 individuals with genomes and
longitudinal phonemes for a year; followed by Arivale, a wellness
company that acquired this type of data on 5000 individuals over the
next 4 years). From these data have come more than 25 peer reviewed
papers. In 2021 he founded the non-profit Phenome Health whose
mission is data-driven health for individuals and big data-approaches
to the four major chronic diseases—diabetes, Alzheimer’s, heart
failure and cancer. Currently we are partnering on these endeavors
with a variety of institutions in the US, Asia and the EU.
Dr. Hood has co-founded 20 biotech companies including Amgen, Applied
Biosystems, Rosetta, Nanostring, Arivale and P4Bios. His many national
and international awards include the Lasker Prize, the Kyoto Prize,
and the National Medal of Science. Currently, he is the CEO of Phenome
Health; Co-Founder and Professor at the Institute of Systems Biology
in Seattle; and Chief Innovation Officer and Distinguished Professor
of the Buck Institute for Research on Aging. Dr. Hood has co-authored
two lay person books, The Code of Codes and The Age of Scientific
Wellness as well as 5 text books on biochemistry, immunology, cell
biology, genetics, and systems biology/systems medicine. He has
published more than 1000 peer-review papers in many different fields.














































