SynBioBeta Speaker
Alice Pettitt
ARIA
Frontier Specialist
Alice works across ARIA's life sciences and AI portfolio, identifying and helping to shape new programme opportunities. Prior to joining ARIA, Alice completed a PhD in Molecular Biophysics at University College London where she combined computational and experimental approaches to characterise intrinsically disordered proteins. Alice also has experience in pre-seed life sciences investing.
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Human Health
From Cells to Patients: Solving the Scale Mismatch in Virtual Biology
Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?
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