SynBioBeta Speaker
Ivan Jayapurna
ARIA
Programme Director
Running a £50m programme to turn proteins into ‘Universal Fabricators’. Today most protein engineers design drugs and enzymes. If successful, programmable proteins (+ reactor flows/fields) will assemble next-gen inorganic and composite materials for electronics, energy, and infrastructure that currently cannot be mass manufactured.
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Human Health
From Cells to Patients: Solving the Scale Mismatch in Virtual Biology
Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?
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