SynBioBeta Speaker
Lauren Greenlee
XPRIZE Foundation
EVP
Lauren Greenlee is the Executive Vice President of the Food + Water + Waste Domain at the XPRIZE Foundation. XPRIZE is the world's leader in designing and operating incentive competitions that set audacious goals, drive technology innovation, and aim to solve humanity's grand challenges. Lauren leads the foundation's work across food, water, and waste and brings 20 years of experience working in national laboratory, academic, and startup environments. Before XPRIZE, Lauren served as the Chief Technology Officer for sHYp, an early-stage startup company developing technology to produce green hydrogen from seawater sources. Prior to sHYp, Lauren spent 11 years leading research programs that centered on materials engineering to address sustainability issues in water, energy, and agriculture. Lauren holds a B.S.E. in Chemical Engineering from the University of Michigan, an M.S. in Environmental Engineering and a Ph.D. in Chemical Engineering from the University of Texas at Austin, and an M.B.A. from the University of Iowa.
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Human Health
From Cells to Patients: Solving the Scale Mismatch in Virtual Biology
Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?
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