SynBioBeta Speaker
Sandy Yao
CZI Biohub
VP, AI, IP & Tech.; CLO
Sandy Yao serves as the Vice President of AI, IP and Technology at the Chan Zuckerberg Initiative and the Chief Legal Officer of Biohub. She oversees the legal and policy work supporting AI, technology and science for the organizations, and leads Biohub's efforts on responsible AI practices.At the intersection of AI and biotech, Sandy highlights emerging opportunities for women leaders to drive innovation and ethical progress. She offers insight into navigating career growth where women can lead the charge that helps shape a more inclusive and impactful future for the field.
SynBioBeta 2026 Tickets are Live
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Sandy
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Human Health
From Cells to Patients: Solving the Scale Mismatch in Virtual Biology
Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?
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