SynBioBeta Speaker
Trevor Nicks
Caravel Bio
Founder & CEO
Trevor is the Founder and CEO of Caravel Bio - a platform company building new protein machines. Caravel’s hybrid approach to protein engineering and scale-up combines the best parts of synthetic and cell-free biology. A decade ago, fresh out of his first biochem class, he helped launch Spira, an IndieBio-backed company that worked on producing proteins in algae. Ultimately, he left Spira to finish undergrad and pursue a PhD in Biotechnology Engineering at Tufts University. His PhD thesis focused on creating tools for engineering bacterial spores as self-assembling, evolvable protein carriers to complement or replace materials science immobilization of proteins. Caravel continues to leverage spores and cell-free systems in new forms of high-throughput, contextual protein evolution for products across health and industrial biology.
SynBioBeta 2026 Tickets are Live
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Trevor
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Human Health
From Cells to Patients: Solving the Scale Mismatch in Virtual Biology
Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?
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