SynBioBeta Speaker

Victoria Mascetti

University of Bristol

Assistant Professor

Dr. Victoria Mascetti is a leading stem cell biologist and honorary Assistant Professor at the University of Bristol, UK, with more than a decade of international experience advancing regenerative medicine and translational research. Her work sits at the forefront of stem cell science, with a strong emphasis on clinical application and commercial innovation.

Dr. Mascetti earned her Ph.D. from the University of Cambridge as a British Heart Foundation scholar, where she investigated the molecular mechanisms governing human pluripotent stem cell maintenance and differentiation into clinically relevant cell types. She went on to Stanford University, USA, supported by a prestigious American Society of Hematology Fellowship, where she expanded her expertise in the developmental biology of tissue-resident stem cells.

In 2019, Dr. Mascetti was awarded a competitive Vice Chancellor’s Fellowship to establish and lead a research group at the University of Bristol's Division of Cardiovascular Sciences. Her team is developing next-generation, stem cell–engineered cardiac patches aimed at repairing congenital heart defects—combining advanced stem cell biology with cutting-edge tissue engineering.

Her scientific leadership has been recognized with multiple international awards, including honors from the International Academy of Cardiovascular Science, the British Society for Cardiovascular Research, and the International Society for Heart Research.

Dr. Mascetti is a trusted expert in applying stem cell science to real-world clinical and commercial challenges. In addition to her academic work, Dr. Mascetti serves as a scientific consultant, advising biotech companies on stem cell strategy, translational research pathways, and product development. Her expertise bridges the gap between scientific discovery and real-world application.

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Fireside Chat

12:00 AM

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8:30 AM

Human Health

From Cells to Patients: Solving the Scale Mismatch in Virtual Biology

Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?

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