SynBioBeta Speaker
Zara Butte
Human Longevity
Physician
Zara Butte, M.D. is a board-certified internal medicine physician and clinical strategist. She practices at Human Longevity, Inc., where she focuses on early disease detection, risk stratification, and advanced diagnostics. Her clinical approach incorporates precision medicine techniques and integrative approaches to health and longevity, especially for women. Dr. Butte also advises companies at various stages on clinical product development, operations, and strategy.
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Human Health
From Cells to Patients: Solving the Scale Mismatch in Virtual Biology
Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?
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