SynBioBeta Speaker
Ewa Lis
Koliber Biosciences
Founder & CEO
Dr. Ewa Lis is the Founder and CEO of Koliber Biosciences, a computational biology company that leverages an advanced AI platform for the discovery and optimization of peptides and proteins. With a rich background in both computer science and biological sciences, Dr. Lis's expertise encompasses large language models, deep learning, data augmentation, graph networks, and various domains of biology and chemistry. Before establishing Koliber Biosciences in 2014, she held key positions at Reveal Biosciences , Life Technologies and Genomatica, where she contributed to the development of diverse technologies ranging from algorithms for pathology tissue classification to tools for genome engineering research and microbial strains for chemical production. Dr. Lis earned her BA in Chemistry from Cornell University and her Ph.D. in Biological Sciences from The Scripps Research Institute.
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Human Health
From Cells to Patients: Solving the Scale Mismatch in Virtual Biology
Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?
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