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SynBioBeta Speaker

Robert Saperstein

DARPA

Deputy Director, BTO

Rob Saperstein, Ph.D., is the deputy director of DARPA’s Biological Technologies Office. He most recently served as a program manager for the Strategic Technology Office starting in June 2018, where he led a portfolio of programs developing novel sensing, communications, and laser-based technologies for mission system applications.Prior to joining DARPA, Saperstein was vice president for research and development in photonics at Ziva Corporation in San Diego, Calif. There he led programs in physical layer encryption and non-traditional optical imaging systems, supported by computational imaging. Saperstein served in senior technical roles in programs on distributed ad hoc beamforming and on minimally invasive, multi-modal neural interfaces.

Sessions Featuring

Robert

This Year

TBD

Session lineup still growing

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Speaker Coming Soon

Fireside Chat

12:00 AM

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8:30 AM

Human Health

From Cells to Patients: Solving the Scale Mismatch in Virtual Biology

Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?

Featuring

Speaker Coming Soon

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