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SynBioBeta Speaker

Ross Uhrich

ARPA-H

Program Manager

Dr .Ross Uhrich is a Board-Certified surgeon, investor, and Program Manager (General Partner) with ARPA-H, a US Government agency created to catalyze transformative health breakthroughs, managing a ~$400M portfolio of revolutionary biotechnology investments.His active funding and management portfolio includes the NITRO Program, which aims to eradicate osteoarthritis through tissue regeneration, the POSEIDON Program, which aims to create an at-home cancer screening test for 30+ cancers using breath and/or urine, and two ARPA-H oncology projects, CODA and SPIKEs, which seek to use synthetic biology to revolutionize cancer care.Prior to ARPA-H, he worked as a Board-Certified Oral & Maxillofacial Surgeon and Assistant Professor of Surgery at Walter Reed National Military Medical Center (WRNMMC) and the Uniformed Services University of the Health Sciences, respectively. In addition to these roles, Dr. Uhrich spent 12 years with the U.S. Navy, finishing his tenure as a Lieutenant Commander.

SynBioBeta 2026 Tickets are Live

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Ross

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Fireside Chat

12:00 AM

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8:30 AM

Human Health

From Cells to Patients: Solving the Scale Mismatch in Virtual Biology

Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?

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