SynBioBeta Speaker
Simone Bianco
Altos Labs
VP, Physics, Molecular & Hybrid Modeling
Dr. Simone Bianco is Vice President of Hybrid AI and Physics Based modeling at the Altos Labs Institute of Computation. Prior to joining Altos, he was a research staff member and manager of the department of Functional Genomics and Cellular Engineering at the IBM Almaden Research Center. He is an expert in computer driven design of biological systems. Dr. Bianco has contributed to the design of vaccines, antivirals, antimicrobials and immunotherapies, and holds several patents in synthetic biology. He is founding PI of the NSF Center for Cellular Construction, which aims at transforming cell biology into an engineering discipline. Dr. Bianco is a TED speaker with over 1M views, recipient of IBM’s Outstanding Research Achievement Award, and an honorary visiting lecturer for the Society for Industrial andApplied Mathematics, for his standing in the field of dynamical systems and commitment to education.
SynBioBeta 2026 Tickets are Live
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Human Health
From Cells to Patients: Solving the Scale Mismatch in Virtual Biology
Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?
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