The next leap in biomanufacturing won’t come from better organisms alone; it will come from better inputs. In this session, Erg Bio explores how rethinking feedstocks is unlocking new pathways to scalable, cost-effective, and sustainable production. Feedstocks that could transcend supply chain issues, those that could enable production at any location and on demand! From alternative carbon sources to waste-derived inputs, advances in feedstock innovation will reshape the emerging trillion-dollar bioeconomy. By aligning biology with abundant, low-cost raw materials, the industry can move beyond traditional constraints and build more resilient supply chains, powering a new generation of biomanufacturing at a global scale.