SynBioBeta Speaker
Aaron Blotnick
SynBioBeta
Bay Area Community Manager
Aaron Blotnick has spent the past decade at the intersection of science, data, and strategy, helping build and scale biotechnology companies across Silicon Valley. He has worked across a range of application areas—including Diagnostics, Synthetic Biology, Cell and Gene Therapy Reagents, and CDMO/CRO services—and has served in roles spanning Research, Data Science, Market Strategy, and Chief of Staff functions. Aaron currently supports a number of initiatives under the dual roles of Consultant at Breakthrough Bio Advisors and SF City Captain for Bits in Bio.
Aaron's graduate works was focused on using molecular labeling techniques (BONCAT) to better understand chronic disease. His postgraduate work continued this use of biological tools into genetic engineering which utilized a proteosomal degradation tool called an Auxin Inducible Degron to understand basic biology of the developing heart.
SynBioBeta 2026 Tickets are Live
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Human Health
From Cells to Patients: Solving the Scale Mismatch in Virtual Biology
Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?
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