SynBioBeta Speaker
Gloria Elliot
ARPA-H
Program Manager
Dr. Gloria Elliott joined ARPA-H as Program Manager in January 2025 and currently manages a portfolio aimed at overcoming the hurdles that prevent access to advanced biological medicines, including cell and gene therapies, organ transplants, and other regenerative therapies. Her previous post was at the Organ Preservation Alliance where she served as president and Chief Science Officer. Prior to that, Elliott was the founding Chief Science Officer of Humanity Bio, a small biotechnology research company focused on human tissue preservation. Elliott is also a professor emerita at the University of North Carolina at Charlotte. Her expertise is in cryobiology and biopreservation technology, including strategies to overcome cold chain. She received her doctorate in mechanical engineering from Michigan State University and completed post-doctoral work at Harvard Medical School and the Massachusetts General Hospital Center for Engineering in Medicine.
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Human Health
From Cells to Patients: Solving the Scale Mismatch in Virtual Biology
Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?
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