SynBioBeta Speaker
Gregory Rieker
University of Col. Boulder
Professor
Greg Rieker is a Provost’s Endowed Chair Professor in Mechanical Engineering at the University of Colorado Boulder. He leads the Precision Laser Diagnostics Laboratory, which aims to understand and improve energy, industrial, and atmospheric systems through laser-based sensing. In particular, the laboratory has spent a decade adapting Nobel prize winning frequency comb laser technology into robust sensors to address emerging challenges, including detecting methane emissions across hundreds of square miles of oil and gas infrastructure, designing hypersonic propulsion systems, and exploring exoplanet atmospheres. Greg earned a BS from the Missouri University of Science and Technology, and MS and PhD degrees from Stanford University. He has affiliations with the National Renewable Energy Laboratory and the National Institute of Standards and Technology. Greg received the NSF CAREER award, the Peter Werle and Hiroshi Tsuji Early Career Scientist Awards, and the Colorado Governor’s Award for High-impact Research. He is a senior member of the National Academy of Inventors, and co-founder and CTO of LongPath Technologies, Inc.
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Human Health
From Cells to Patients: Solving the Scale Mismatch in Virtual Biology
Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?
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