
SynBioBeta Speaker
Deepti Tanjore
Lawrence Berkeley Nat'l Lab.
Director, ABPDU
Deepti Tanjore is Director of the ABPDU and Head of the Department, Process Engineering and Analytics at Berkeley Lab. She interfaces with several scientists from industry, academia, and start-ups in strategizing and resolving scale-up challenges for their synthetic biology-based technologies. Her research focuses on developing self-driving bioreactor capabilities by modeling the impact of bioprocess conditions on microbial heterogeneity and developing in-line analytical tools for real-time adaptation of process development. She has a PhD from Penn State University in Biological Engineering, BTech from Andhra University in Chemical Engineering, and an MBA from Haas School of Business.
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Human Health
From Cells to Patients: Solving the Scale Mismatch in Virtual Biology
Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?
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