SynBioBeta Speaker

Marieke Klijn

Delft University of Technology

Associate Professor

Implementation of process analytical technology into bioprocesses to enable accelerated process understanding and scale-up

SynBioBeta 2026 Tickets are Live

Confirmed Speakers

Sessions Featuring

Marieke

This Year

Breakout Session

4:30 PM

-

5:15 PM

Tools & Tech

Your Cells Are Talking, Are You Listening? Measuring Physiology at Industrial Scale

Standard bioreactors often lack the instrumentation required to rapidly monitor cell physiology, leaving critical gaps in our understanding of scale-up dynamics. This session presents active projects from the Schmidt Sciences’ Sensors for Biomanufacturing Program designed to address this challenge through novel sensing modalities. Spanning from near real-time intracellular measurements to non-invasive off-gas fingerprinting, the panel brings together technology developers and industrial bioprocess experts to discuss the translation of these tools from the lab to the plant floor. Together, we will critically evaluate the utility of high-dimensional metabolic data and explore the engineering requirements for integrating physics-based sensors and machine learning into existing biomanufacturing workflows.

Purchase Pass

Breakout Session

4:30 PM

-

5:15 PM

Tools & Tech

Your Cells Are Talking, Are You Listening? Measuring Physiology at Industrial Scale

Standard bioreactors often lack the instrumentation required to rapidly monitor cell physiology, leaving critical gaps in our understanding of scale-up dynamics. This session presents active projects from the Schmidt Sciences’ Sensors for Biomanufacturing Program designed to address this challenge through novel sensing modalities. Spanning from near real-time intracellular measurements to non-invasive off-gas fingerprinting, the panel brings together technology developers and industrial bioprocess experts to discuss the translation of these tools from the lab to the plant floor. Together, we will critically evaluate the utility of high-dimensional metabolic data and explore the engineering requirements for integrating physics-based sensors and machine learning into existing biomanufacturing workflows.

Purchase Pass

TBD

Session lineup still growing

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Featuring

Speaker Coming Soon

Fireside Chat

12:00 AM

-

8:30 AM

Human Health

From Cells to Patients: Solving the Scale Mismatch in Virtual Biology

Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?

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Featuring

Speaker Coming Soon

Previous Speakers Include