SynBioBeta Speaker
Samuel Sjayakanthan
Vandstrom
Research Director
Samuel Jayakanthan leads the Protein Sciences team at Vandstrom, a company revolutionizing water desalination by harnessing the unique filtration properties of proteins. With a background that spans biophysics, structural biology, and protein engineering, he seeks to leverage innovative technologies to help solve the world’s environmental crises and push humanity forward. He is passionate about integral membrane proteins and how harnessing their unrivaled capabilities can help solve some of the world’s toughest challenges, from water scarcity to the recovery of rare earth elements and critical minerals.
SynBioBeta 2026 Tickets are Live
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Human Health
From Cells to Patients: Solving the Scale Mismatch in Virtual Biology
Drug discovery often measures biology at the cell level while interventions work at the tissue, organ, or whole-patient scale. This mismatch can make accurate cell-level predictions irrelevant in the clinic. This session dives into strategies to bridge that gap: multiscale modeling that nests single-cell dynamics within organ-level simulations, spatial transcriptomics that preserve context, and surrogate models that translate cell-level outputs into clinical biomarkers. Speakers will ask: how do we ensure virtual biology reflects not just what cells do in isolation, but how biology behaves in the real complexity of patients?
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