SynBioBeta Speaker

Leroy Hood

Co-founder and Professor

ISB

May 2026, SynBioBeta

Speaker

Dr. Lee Hood is a world-renowned scientist and recipient of theNational Medal of Science in 2011. Dr. Leroy Hood co-founded theInstitute for Systems Biology (ISB) in 2000 and served as its firstPresident from 2000-2017. In 2016, ISB affiliated with Providence St.Joseph Health (PSJH) and Dr. Hood became PSJH’s Senior Vice Presidentand Chief Science Officer. He is also Chief Strategy Officer andProfessor at ISB. Dr. Hood is a member of the National Academy ofSciences, the National Academy of Engineering, and the NationalAcademy of Medicine. Of the more than 6,000 scientists worldwide whobelong to one or more of these academies, Dr. Hood is one of only 20people elected to all three. He is also in the Inventor Hall of Famefor the automated DNA sequencer.He received his MD from Johns Hopkins University School of Medicineand his PhD in biochemistry from Caltech. Dr. Hood was a facultymember at Caltech from 1967-1992, serving for 10 years as the Chair ofBiology. During this period, he and his colleagues developed foursequencer and synthesizer instruments that paved the way for the HumanGenome Project’s successful mapping and understanding of the humangenome. He and his students also deciphered many of the complexmechanisms of antibody diversification. 1992, Dr. Hood founded andchaired the Department of Molecular Biotechnology at the University ofWashington, the first academic department devoted tocross-disciplinary biology and individuals from this departmentdeveloped pioneering strategies in genomics, proteomics and cellbiology. Dr. Hood then in 2000 began pioneering many applications ofsystems biology to ordinary biology and disease (neurodegeneration,cancer).  While at Systems biology, in 2014 he pioneered the study ofdata-driven health in individuals (108 individuals with genomes andlongitudinal phonemes for a year; followed by Arivale, a wellnesscompany that acquired this type of data on 5000 individuals over thenext 4 years). From these data have come more than 25 peer reviewedpapers. In 2021 he founded the non-profit Phenome Health whosemission is data-driven health for individuals and big data-approachesto the four major chronic diseases—diabetes, Alzheimer’s, heartfailure and cancer. Currently we are partnering on these endeavorswith a variety of institutions in the US, Asia and the EU.Dr. Hood has co-founded 20 biotech companies including Amgen, AppliedBiosystems, Rosetta, Nanostring, Arivale and P4Bios. His many nationaland international awards include the Lasker Prize, the Kyoto Prize,and the National Medal of Science. Currently, he is the CEO of PhenomeHealth; Co-Founder and Professor at the Institute of Systems Biologyin Seattle; and Chief Innovation Officer and Distinguished Professorof the Buck Institute for Research on Aging. Dr. Hood has co-authoredtwo lay person books, The Code of Codes and The Age of ScientificWellness as well as 5 text books on biochemistry, immunology, cellbiology, genetics, and systems biology/systems medicine. He haspublished more than 1000 peer-review papers in many different fields.

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