SynBioBeta Speaker
Barry Bunin
Founder & CEO
CDD
May 2026, SynBioBeta
Speaker
Barry A. Bunin, Ph.D. is the CEO of Collaborative Drug Discovery. Dr. Bunin has overseen $100 million in business transactions over the last two decades. CDD Vault hosts over 4 billion experimental SAR data points searched over 10 million times by scientists daily around the world doing…collaborative drug discovery. Recent innovations include generative bioisosteres, ultrafast deep learning similarity search and chemically aware biologics capabilities (for example for each atom in ADCs).Prior to CDD, he was an Entrepreneur in Residence with Eli Lilly & Co. Dr. Bunin is on a patent for Kyprolis™ (Carfilzomib for Injection) — a selective proteasome inhibitor that received accelerated FDA approval for the treatment of patients with multiple myeloma that was widely viewed as the centerpiece of Amgen’s $10.4 Billion acquisition of Onyx Pharmaceuticals.Dr. Bunin was the founding CEO, President, & CSO of Libraria (now Eidogen-Sertanty). At Libraria, he led a team that integrated exhaustive reaction capture (synthetic chemistry) with gene-family wide SAR capture (medicinal chemistry). In the lab, Dr. Bunin did medicinal synthetic chemistry developing patented new chemotypes for protease inhibition at Axys Pharmaceuticals (now Celera) and RGD mimics to inhibit GP-IIbIIIa at Genentech.Dr. Bunin received his B.A. from Columbia University and his Ph.D. from UC Berkeley, where he synthesized and tested the initial 1,4-benzodiazepine libraries with Professor Jonathan Ellman. On the scientific side, he co-authored 3 books: “Chemoinformatics: Theory, Practice, and Products” (Springer-Verlag), a text that overviews modern chemoinformatics technologies, and “The Combinatorial Index” (Academic Press), a widely used text on high-throughput chemical synthesis, and most recently self-published the collaborative book: “Inside CDD Vault: A Different Kind of Silicon Valley Success Story (Behind the Code: The Human Side of Collaborative Drug Discovery)” available on Amazon.
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