SynBioBeta Speaker
Eriona Hysolli
Co-founder
Manhattan Genomics
May 2026, SynBioBeta
Speaker
Eriona Hysolli completed her PhD work at Yale University - Genetics Department, working on derivation and characterization of human induced pluripotent stem cells (iPSCs) and the role of microRNAs in this process. She went on to do postdoctoral training in George Church’s lab where she published studies on genomically-recoded bacteria - mammalian cells co-culture systems, multiplex genome engineering approaches for human genome recoding. Furthermore, in his laboratory, she derived the first reprogrammed African elephant iPSCs, and led the woolly mammoth de-extinction efforts, work that she carried forward at Colossal Biosciences as Head of Biological Sciences. There she led the efforts to de-extinct the woolly mammoth, working on Proboscidean comparative genomics and reference genome assemblies, including a first attempt at the woolly mammoth reference genome with long-read sequencing, multiplex editing in embryo for trait engineering and de-extinction, first ever generation of Asian elephant iPSCs, as well as biobanking efforts for elephant conservation. She is now a co-founder and CSO of Manhattan Genomics, a company with a mission to prevent genetic diseases by targeting disease alleles for correction at the embryo stage. Eriona is also a Time100 Next recipient.
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